Do you mind?

I was surfing the net when I found this beauty...http://www.youtube.com/watch?v=U8nv7sOj7yM&feature=relmfu i've watched many of his videos before (cause they're fabulous), but this one really has me thinking. I deffers struggle to answer appropriately when someone asks "Do you mind?" and to be honest kind of think of it as a southern bitch phrase, similar to bless your heart. your thoughts?